2020-02-23 09:46:13 阅读：958522
Health FDA, CDC Say E. Coli Outbreak is Over
Jonathan Ernst—Reuters Sylvia Burwell, Secretary of Health and Human Services As we think about the question of what worked and what didnt, we have to remember that this was an unprecedented challenge in scope, scale and clinical complexity. Its something that required the whole of government to respond, and I think we are more prepared to do that a year later. MORE: The Ebola Fighters First, our clinical approach to treating Ebola in a typical intensive U.S. hospital setting posed different challenges. While we had years of experience through MSF (Doctors Without Borders) and others who had helped in West Africa, they were treating Ebola in a very different clinical setting. So applying what we learned about doing so in our clinical setting was a place where improvement was needed, and it was quickly made. We always want to focus on correcting errors of what worked and what didnt, and we did that on an ongoing basis. We saw that when the CDC made immediate changes to the guidelines for personal protective equipment. Second, we found out that we needed more specialized treatment centers for Ebola and other special pathogens for this type of intensive, complex clinical treatment. Im still concerned about Ebola because we still have cases in West Africa. And as a nation, we are concerned about the next thing. We cant just fund efforts like Ebola treatment centers at times when there is a critical problem. We need to make sure we are continuing to do that on an ongoing basis. MORE: WHO Politics Interfered With Ebola Response, Panel Says Bryan Schutmaat for TIME Dr. Tom Frieden, director of the Centers for Disease Control and Prevention (CDC) To me, there are three main lessons in the Ebola epidemic. First, every single country needs a strong system to find and stop threats. Second, when countries are overwhelmed, the world needs to be able to surge in rapidly. Third, infection control in hospitals has to get better. Get our Health Newsletter. Sign up to receive the latest health and science news, plus answers to wellness questions and expert tips.
For your security, we've sent a confirmation email to the address you entered. Click the link to confirm your subscription and begin receiving our newsletters. If you don't get the confirmation within 10 minutes, please check your spam folder. Clearly, we wish that the hospital [in Dallas] had diagnosed Mr. Duncan the first time he went in with a temperature of 103 F and a history of having come from Liberia. Clearly, despite the efforts of the nurses to avoid infection, two nurses got infected. That was not acceptable. Therefore we rapidly intensified our recommendations for infection control with respect to Ebola. We worked extensively with hospitals around the country and invested $340 million to enhance state and local health care systems preparedness. We designated facilities and funded more than 55 local and regional Ebola treatment centers. One of the things we learned from this epidemic is how challenging it is to care for patients with Ebola safely. CDC staff had cared for patients with Ebola in Africa in the 70s, 80s and 90s, and we had never seen infections in our staff. But things were different this time around. For one, there was much more explosive diarrhea in patients than we had seen before. Second, the nursing care in the U.S. is much more intensivewith nurses [frequently] turning and caring for patientsthan it is in the Ebola unit in Africa. Third, in retrospect, we should have known better. There are 75,000 deaths each year from infections spread in hospitals in the U.S.. We know no matter how good our recommendations for hand washing and personal protective equipment are, we have to have a large margin of safety for how they will actually be implemented in the field. If we look back at the past year, there are things science learned that we didnt know at the time, so there are things we could not have done differently. There are things that with 20-20 hindsight, if we had known everything that we know now, we could have perhaps been more effective. Then there are the things, even knowing what we knew then, we could have done differently. Once we knew the first nurse was infected, we should not have allowed Amber Vinson to fly, even though she didnt have a fever. Because she had the same exposure and should have been considered high risk, we should not have allowed her to fly. Spotlight Story Kobe Bryant Had a Singular Impact on His Game and the World Bryant died in a helicopter crash near Los Angeles on Sunday, along with his daughter Gianna Now, in the U.S., we need to guard against complacency. There will always be new infections. We know we have to keep our public health system strong and prepared to respond to everyday threats so we can surge up when needed to deal with an emergency. Alex Wong—Getty Images Dr. Anthony Fauci, director National Institute for Allergy and Infectious Diseases The lesson I learned was more a medical lesson than anything else. I was under what now turns out to be the misimpression that if you can get every Ebola patient into an intensive care setting, keep their fluids and electrolytes properly balanced and not allow them to develop hypotension or shockif you are just able to monitor themthat inevitably they will be fine. What I learned from taking care of the second patient at the National Institutes of Health (NIH) is that there is a small subset of patients in whom the virus is so virulently attacking the body that everything starts to collapse, even if you give them optimum fluid replacement therapy. This happened to me and my colleagues as we took care of our second patient over a period of two and a half weeks in March. The person [a healthcare worker who was infected while working in Sierra Leone and who remains anonymous] came in and was still conscious, but clearly very, very sick. We put in the appropriate IV access, the appropriate tubes and intensive care paraphernalia and kept his fluids perfectly in balance. He never went into shock. And even though he had massive diarrhea and vomiting, we meticulously kept up his fluids. We thought, Okay, we just need to do this for a while and he will be home free. Then, to our amazement, he went into
respiratory failure, requiring emergency intubation. It was the virus attacking his lungs. Then he went into renal failurehow could that possibly be? Then he had cardiovascular abnormalities. Finally he developed severe inflammation of the brain. Related Health Iowa Girl Blinded After Contracting the Flu There were two or three of us in the room at any given moment, all day and all night, and he survived. Otherwise he would have died five times over. What this tells us is that for a small subset of people, being treated in a very intensive care setting is necessary to save their lives. The lesson is that the next time something like this occursespecially if youre dealing with a disease that can spread among healthcare workersyou really require training and proper equipment. We would have been in danger of getting infected if we werent very, very well practiced in how to put on and take off the personal protective equipment and how to give intensive care to someone who is desperately ill. The lesson is that not everybody and not every hospital can take care of a desperately ill Ebola patient in an intensive care setting. There is a big difference between admitting somebody and isolating them when they are not that sick, versus really administering minute-by-minute life-saving therapy with all the proper machines, respirators and pick lines. Youre not going to do that in a general hospital. That was patently obvious to me as I went through the care of this patient day and night. In a broad sense, we need more than just a few hospitalsin the case of Ebola, NIH, Emory, Nebraska and Bellevuein case there is a large number of patients. Taking care of people in intensive care requires more than just superficial training. We trained and trained and trained for that, so when we had to do it, it came naturally. You dont just pull up a website and ask how to do it. I never felt that you could have many, many, many hospitals be able to do the kinds of things we did at NIH and that Nebraska, Emory and Bellevue did. I never felt comfortable with that. Related Health Texas Teen Youngest Vaping Victim I also found it really good when Ron Klain came in as Ebola response coordinator. He had a extraordinarily positive capability of coordinating a group of very powerful, independent-minded agencies. Without telling anybody what to do, he created a great forum for communication, cooperation, collaboration and synergy. So I think having someone like that is a really good idea. Kazuhiro Nogi—AFP/Getty Images Nicole Lurie, assistant secretary for preparedness and response Health and Human Services We learned a whole lot and are in a far, far better place now than we were a year ago. We learned that its complicated to take care of Ebola patients. It requires a hospital and staff with really great training in infection control practices and the ability to deliver really sophisticated care while maintaining isolation and infection control practices to the highest degree. Thats why every state now has at least one hospital that can assess potential Ebola patients. We have 55 Ebola treatment centers across the country. And we have a regional system of nine regional centers that could treat Ebola, with more specialized capacities to treat other highly infectious diseases as well. In some sense, we were really quite surprised to learn last year that many health professionals were never really taught how to put on and take off personal protective equipment in the safest way possible. Taking care of very sick Ebola patients requires very specialized care and specialized training. From that perspective, when you have designated centers for Ebola treatment, the more experience people have, the better and safer care they can provide. That was certainly a lesson learned, and its a really important one. The other lesson, and the reason we created the designated centers, was that in the beginning, many hospitals didnt want to take care of patients with Ebola. They were terrified, their staffs were terrified and the public and the community were terrified. They were very, very worried, frankly, that they would lose business. So many hospitals sought to avoid it. So it was probably unrealistic [to expect every hospital to be able to care for Ebola patients]. There are certainly hospitals that cant do it and other hospitals that dont want to do it. The demands of taking care of an Ebola patient are so intensive that a number of hospitals could not carry on normal business functions. The lesson learned is that we need designated Ebola centers to do it. But that requires funding. We now have funding in place to support the regional network of centers financially for the next five years. But our country has a big national attention deficit. When things recede in the rear-view mirror, we like to forget about them, forget that they need funding and forget the need to practice and exercise and train. Were going to have to find ways to sustain the network far into the future. Because its not a matter of ifbut whenthe next really scary infectious disease comes. 宝宝平特 Contact us at firstname.lastname@example.org.